Hepatitis after gene therapy, what are the possible causes?

Abstract excerpt

Hepatitis is a common adverse event following gene therapy for haemophilia, often associated with a loss of transgene expression. Investigating the potential causes and implications of this is crucial for the overall success of treatment. Gene therapy trials using adeno-associated virus (AAV) vectors have demonstrated promising results marked by increases in factor FVIII and FIX levels and reductions in episodes...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Viral gastroenteritis research and epidemiology
• Share to Viral Infections and Immunology Research
• Share to Virus-based gene therapy research