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Determining the effects of genetic linkage when using a combination of STR and SNP loci for kinship testing.

Legal medicine (Tokyo, Japan) - 1 Jul 2024

Yang Da, Ma Sheng Xuan, Zhao Guo Liang, Gao Ao, Xu Zhao Kun

Abstract excerpt

The pedigree likelihood ratio (LR) can be used for determining kinship in the forensic kinship testing. LR can be obtained by analyzing the DNA data of Short tandem repeat (STR) and single nucleotide polymorphism (SNP) loci. With the advancement of biotechnology, increasing number of genetic markers have been identified, thereby expanding the pedigree range of kinship testing. Moreover, some of the loci are...

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PMID: 38599008
DOI: 10.1016/j.legalmed.2024.102441

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