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Resolving kinship degrees with identity-by-descent coefficients: Limits and insights from a simulation study.

Forensic science international - 1 Dec 2025

Wang Haoyu, Wei Yifan, Shan Tiantian, Yang Chun, Cai Yuntao, Hu Yuhan, Zhu Qiang, Zhang Ji

Abstract excerpt

Kinship analysis in forensic genetics often requires precise determination of relatedness degrees rather than existence of kinship. While identity-by-descent (IBD) coefficients are widely used, their discriminatory power for distinguishing relatedness degrees under a likelihood ratio (LR) framework remains inadequately characterized, particularly for distant relatives. In this study, we developed a maximum LR...

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PMID: 40945290
DOI: 10.1016/j.forsciint.2025.112647

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