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Molecular patterns of resistance to immune checkpoint blockade in melanoma

9 Apr 2024

Abstract excerpt

Abstract Immune checkpoint blockade (ICB) has improved outcome for patients with metastatic melanoma but not all benefit from treatment. Several immune- and tumor intrinsic features are associated with clinical response at baseline. However, we need to further understand the molecular changes occurring during development of ICB resistance. Here, we collect biopsies from a cohort of 44 patients with melanoma after...

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PMID: 38594286
DOI: 10.1038/s41467-024-47425-y

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