Article
Real-world data of poly (ADP-ribose) polymerase inhibitor response in Japanese patients with ovarian cancer.
Cancer medicine - 1 Apr 2024
Uekusa Ryosuke, Yokoi Akira, Watanabe Eri, Yoshida Kosuke, Yoshihara Masato, Tamauchi Satoshi, Shimizu Yusuke, Ikeda Yoshiki, Yoshikawa Nobuhisa, Niimi Kaoru, Suzuki Shiro, Kajiyama Hiroaki
Abstract excerpt
BACKGROUND: Poly (ADP-ribose) polymerase (PARP) inhibitors have been increasingly used in the treatment of ovarian cancer, with BRCA positivity and homologous recombination deficiency (HRD) being common biomarkers used for predicting their efficacy. However, given the limitations of these biomarkers, new ones need to be explored. METHODS: This retrospective study included 181 ovarian cancer patients who received...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
