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Article

Tumor suppressor role of the complement inhibitor CSMD1 and its role in TNF-induced neuroinflammation in gliomas.

Journal of experimental & clinical cancer research : CR - 1 Apr 2024

Tuysuz Emre Can, Mourati Eleni, Rosberg Rebecca, Moskal Aleksandra, Gialeli Chrysostomi, Johansson Elinn, Governa Valeria, Belting Mattias, Pietras Alexander, Blom Anna M

Abstract excerpt

BACKGROUND: The complement inhibitor CSMD1 acts as a tumor suppressor in various types of solid cancers. Despite its high level of expression in the brain, its function in gliomas, malignant brain tumors originating from glial cells, has not been investigated. METHODS: Three cohorts of glioma patients comprising 1500 patients were analyzed in our study along with their clinical data. H4, U-118 and U-87 cell lines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38561856
DOI: 10.1186/s13046-024-03019-6
PMCID: PMC10986120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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