Article
The Effective Inhibitory Concentration of Interferon-β Correlates with Infectivity and Replication Fitness of SARS-CoV-2 Variants.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jul 2024
Singh Janmejay, Anantharaj Anbalagan, Kumar Parveen, Pandey Rajesh, Pandey Anil Kumar, Medigeshi Guruprasad R
Abstract excerpt
India saw a spike in COVID-19 cases in early 2023, and this wave of infection was attributed to XBB sublineages of SARS-CoV-2 Omicron variant. The impact of XBB wave was significantly shorter with low burden of severe cases or hospitalization as compared with previous SARS-CoV-2 variants of concern. Although a combination of old and new mutations in the spike region of XBB.1.16 variant led to a drastic reduction...
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