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Article

Targeting BCR-ABL1-positive leukaemias: a review article

1 Jan 2023

Abstract excerpt

gene and resulting BCR::ABL1 oncoprotein in chronic myeloid leukaemia (CML) and Philadelphia chromosome-positive (Ph+) acute leukaemias, has led to treatment advances associated with exceptional improvements in patient outcomes with normal life expectancy for many patients with chronic phase (CP-)CML. However, despite these major therapeutic advances, the management of Ph+ leukaemias remains complex, with...

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PMID: 38550948
DOI: 10.1017/pcm.2023.9

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