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Article

White-Brown switching controls phenotypic plasticity and virulence of Candida auris

1 Jul 2025

Abstract excerpt

The skin-tropic human fungal pathogen Candida auris can cause life-threatening infections of high mortality in healthcare settings. Clinical isolates display a pronounced heterogeneity in virulence traits, such as antifungal susceptibility, stress adaptation, and growth fitness. However, the mechanistic bases underlying intraspecies variations remain enigmatic. Here, we show that C. auris cell populations...

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PMID: 40638387
DOI: 10.1016/j.celrep.2025.115976

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