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High Ki67 Gene Expression Is Associated With Aggressive Phenotype in Hepatocellular Carcinoma

21 Mar 2024

Abstract excerpt

Background: Hepatocellular carcinoma (HCC) with high Ki67 protein expression, the most commonly used cell proliferation marker, is associated with an aggressive biologic phenotype; however, conventional immunostaining is hampered by variability in institutional protocol, specific antibody probe, and by assessor subjectivity. To this end, we hypothesized that Ki67 gene ( MKi67 ) expression would identify highly...

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PMID: 38545476
DOI: 10.14740/wjon1751

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