Article
Neuroprotective Effects of the Nutraceutical Dehydrozingerone and Its C2-Symmetric Dimer in a Drosophila Model of Parkinson's Disease.
Biomolecules - 24 Feb 2024
Setzu Maria Dolores, Mocci Ignazia, Fabbri Davide, Carta Paola, Muroni Patrizia, Diana Andrea, Dettori Maria Antonietta, Casu Maria Antonietta
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons responsible for unintended or uncontrollable movements. Mutations in the leucine-rich repeat kinase 2 locus contribute to genetic forms of PD. The fruit fly Drosophila melanogaster carrying this mutation (LRRK2-Dm) is an in vivo model of PD that develops motor impairment and stands for an eligible...
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