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Amplification of different satellite-DNAs in prostate cancer

21 Mar 2024

Abstract excerpt

In various solid tumors and corresponding cell lines, prior research has identified acquired copy number variations (CNVs) encompassing centromeric satellite-DNA sequences. This observation emerged from the application of centromeric probes (satellite-DNA) as controls in molecular cytogenetic investigations and diagnostics, although these accounts were largely anecdotal. In this study, we conducted a systematic...

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PMID: 38522124
DOI: 10.1016/j.prp.2024.155269

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