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Assessment for 11q and other chromosomal aberrations in large B-cell/high-grade B cell lymphomas of germinal center phenotype lacking BCL2 expression.

Cancer genetics - 1 Jun 2024

Ho Chia-Chen, Naresh Kikkeri, Liu Yajuan, Wu Yu, Gopal Ajay K, Eckel Ashley M

Abstract excerpt

The WHO classifications of hematolymphoid malignancies have recognized several distinct entities within the large B cell lymphomas, including the more recently described high-grade B cell lymphoma with 11q aberration (HGBCL-11q). We utilized genomic array to assess for chromosome 11q abnormalities in a broad set of aggressive B cell lymphomas from 27 patients with a focus on younger adults. The findings suggest...

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Share to Aged, 80 and over
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

Share to Germinal Center

Share to In Situ Hybridization, Fluorescence

Share to Lymphoma, Large B-Cell, Diffuse

Share to Proto-Oncogene Proteins c-bcl-2

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Source

Identifiers

PMID: 38520765
DOI: 10.1016/j.cancergen.2024.03.001

Genes

BCL2
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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