Article
High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition.
Blood - 8 Jan 2026
Ronceray Leila, Huibers Minke H W, Reutter Katrin, Abla Oussama, Andrés Mara, Balagué Olga, Csóka Monika, Gilad Gil, Hagleitner Melanie M, Hori Daiki, Hjalgrim Lisa L, Jazbec Janez, Klapper Wolfram, Nakazawa Atsuko, Verdú-Amorós Jaime, von Mersi Hannah, Wössmann Wilhelm, Xavier Ana C, Burkhardt Birgit, Salaverria Itziar, Attarbaschi Andishe
Abstract excerpt
ABSTRACT: High-grade B-cell lymphoma with 11q aberration (HGBCL-11q) is a rare pediatric non-Hodgkin lymphoma. This study assessed outcome in 90 children with HGBCL-11q. With survival rates ≥95%, patients with HGBCL-11q and no predisposition are candidates for deescalated therapy in future prospective trials.
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