Article
Germline pathogenic variants associated with triple-negative breast cancer in US Hispanic and Guatemalan women using hospital and community-based recruitment strategies.
Breast cancer research and treatment - 1 Jun 2024
Godinez Paredes Jesica M, Rodriguez Isabel, Ren Megan, Orozco Anali, Ortiz Jeremy, Albanez Anaseidy, Jones Catherine, Nahleh Zeina, Barreda Lilian, Garland Lisa, Torres-Gonzalez Edmundo, Wu Dongjing, Luo Wen, Liu Jia, Argueta Victor, Orozco Roberto, Gharzouzi Eduardo, Dean Michael
Abstract excerpt
PURPOSE: Recruit and sequence breast cancer subjects in Guatemalan and US Hispanic populations. Identify optimum strategies to recruit Latin American and Hispanic women into genetic studies of breast cancer. METHODS: We used targeted gene sequencing to identify pathogenic variants in 19 familial breast cancer susceptibility genes in DNA from unselected Hispanic breast cancer cases in the US and Guatemala....
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