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Food preference-based screening method for identification of effectors of substance use disorders using Caenorhabditis elegans

19 Mar 2024

Abstract excerpt

Substance use disorder (SUD) affects over 48 million Americans aged 12 and over. Thus, identifying novel chemicals contributing to SUD will be critical for developing efficient prevention and mitigation strategies. Considering the complexity of the actions and effects of these substances on human behavior, a high-throughput platform using a living organism is ideal. We developed a quick and easy screening assay...

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PMID: 38514005
DOI: 10.1016/j.lfs.2024.122580

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