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Added Value of 13C Analysis in Breath Tests in H2-Negative Subjects to Diagnose Lactose Malabsorption: A Proof of Concept Study.

Digestive diseases and sciences - 1 Jun 2024

Balsiger Lukas Michaja, Houben Els, Vanuytsel Tim, van Ranst Marc, Tack Jan, Verbeke Kristin

Abstract excerpt

INTRODUCTION: Diagnosing lactose malabsorption is usually based on hydrogen excretion in breath after a lactose challenge. However, a proportion of subjects with lactose malabsorption will not present a rise in hydrogen. Measuring excretion of methane or stable isotope labeled 13CO2 after ingestion of 13C-lactose has been proposed to mitigate this problem. OBJECTIVE: The aim of the study was to assess the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38499733
DOI: 10.1007/s10620-024-08304-0
PMCID: PMC7616739

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