Article
Association of Polymorphic Variants of TCF7L2 and PPARG Genes with Metabolic Markers in Patients with Early Disorders of Carbohydrate Metabolism.
Bulletin of experimental biology and medicine - 1 Feb 2024
Isakova D N, Kolomeichuk S N, Petrova Yu A, Lyapina M V, Troshina I A, Voronin K A, Petrov I M
Abstract excerpt
We performed complex analysis of the association of polymorphic variants rs7903146 of the TCF7L2 gene and rs1801282 of the PPARG gene with metabolic parameters, insulin resistance, and β-cell function in a group of patients with early signs of carbohydrate metabolism disturbances in a sample of Tyumen citizens. The study group consisted of 64 people (39 women, 25 men) aged 40-70 years. The distribution of...
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