Article
Prediction of virus–host interactions and identification of hot spot residues of DENV-2 and SH3 domain interactions
14 Mar 2024
Abstract excerpt
Dengue virus, particularly serotype 2 (DENV-2), poses a significant global health threat, and understanding the molecular basis of its interactions with host cell proteins is imperative for developing targeted therapeutic strategies. This study elucidated the interactions between proline-enriched motifs and Src homology 3 (SH3) domain. The SH3 domain is pivotal in mediating protein-protein interactions,...
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