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Multiple cancer cell types release LIF and Gal3 to hijack neural signals

11 Mar 2024

Abstract excerpt

Neural signals can significantly influence cancer prognosis. However, how cancer cells may proactively modulate the nervous system to benefit their own survival is incompletely understood. In this study, we report an overlapping pattern of brain responses, including that in the paraventricular nucleus of the hypothalamus, in multiple mouse models of peripheral cancers. A multi-omic screening then identifies...

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PMID: 38467743
DOI: 10.1038/s41422-024-00946-z

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