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Article

Sex-specific Stone-forming Phenotype in Mice During Hypercalciuria/Urine Alkalinization.

Laboratory investigation; a journal of technical methods and pathology - 1 May 2024

Awuah Boadi Eugenia, Shin Samuel, Choi Bok-Eum, Ly Khanh, Raub Christopher B, Bandyopadhyay Bidhan C

Abstract excerpt

Sex differences in kidney stone formation are well known. Females generally have slightly acidic blood and higher urine pH when compared with males, which makes them more vulnerable to calcium stone formation, yet the mechanism is still unclear. We aimed to examine the role of sex in stone formation during hypercalciuria and urine alkalinization through acetazolamide and calcium gluconate supplementation,...

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Identifiers

PMID: 38452902
DOI: 10.1016/j.labinv.2024.102047
PMCID: PMC11103239

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