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Assessing immunogenicity of CRISPR-NCas9 engineered strain against porcine epidemic diarrhea virus

2 Mar 2024

Abstract excerpt

Porcine epidemic diarrhea (PED) caused by porcine epidemic diarrhea virus (PEDV), is an acute and highly infectious disease, resulting in substantial economic losses in the pig industry. Given that PEDV primarily infects the mucosal surfaces of the intestinal tract, it is crucial to improve the mucosal immunity to prevent viral invasion. Lactic acid bacteria (LAB) oral vaccines offer unique advantages and...

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PMID: 38430229
DOI: 10.1007/s00253-023-12989-0

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