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Article

Knocking out the LRRK2 gene increases sensitivity to wavelength information in rats.

Scientific reports - 29 Feb 2024

Østergaard Freja Gam

Abstract excerpt

Leucine-rich repeat kinase 2 (LRRK2) is a gene related to familial Parkinson's disease (PD). It has been associated with nonmotor symptoms such as disturbances in the visual system affecting colour discrimination and contrast sensitivity. This study examined how deficiency of LRRK2 impacts visual processing in adult rats. Additionally, we investigated whether these changes can be modelled in wild-type rats by...

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Identifiers

PMID: 38424139
DOI: 10.1038/s41598-024-55350-9
PMCID: PMC10904730

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