Article
The investigation of killer-cell immunoglobulin-like receptors (KIRs) and their HLA ligands in Iranian patients with myasthenia gravis.
Clinical neurology and neurosurgery - 1 Mar 2024
Jalalvand Mobina, Beigmohammadi Fereshteh, Soltani Samaneh, Ehsan Soroush, Rajabkhah Sahebeh, Madreseh Elham, Akhtari Maryam, Jamshidi Ahmadreza, Farhadi Elham, Mahmoudi Mahdi, Nafissi Shahriar
Abstract excerpt
BACKGROUND: Myasthenia gravis (MG) is a disabling disease with the underlying pathophysiology of auto-antibodies attacking the postsynaptic acetylcholine receptors of neuromuscular junctions causing muscle weakness. Natural killer (NK) cells are innate immune cells that play an important regulative role in immune responses. The human killer-cell immunoglobulin-like receptors (KIRs) family is one of the receptors...
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