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Hypermethylated genome of a fish vertebrate iridovirus ISKNV plays important roles in viral infection

28 Feb 2024

Abstract excerpt

Iridoviruses are nucleocytoplasmic large dsDNA viruses that infect invertebrates and ectothermic vertebrates. The hypermethylated genome of vertebrate iridoviruses is unique among animal viruses. However, the map and function of iridovirus genomic methylation remain unknown. Herein, the methylated genome of Infectious spleen and kidney necrosis virus (ISKNV, a fish iridovirus), and its role in viral infection,...

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PMID: 38413759
DOI: 10.1038/s42003-024-05919-x

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