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Elucidating Hedgehog pathway's role in HNSCC progression: insights from a 6-gene signature

26 Feb 2024

Abstract excerpt

With the emergence of targeted inhibition strategies for Hedgehog signaling in cancer, multiple Hedgehog signaling pathway-related biomarkers have become the focus of research. SsGSEA algorithm was employed to analyze the Hedgehog pathway scores of samples in TCGA-HNSC dataset and divide them into two groups. Weighted co-expression network analysis was performed to identify modules strongly associated with the...

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PMID: 38409358
DOI: 10.1038/s41598-024-54937-6

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