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Protein Profiling of Placental Extracellular Vesicles in Gestational Diabetes Mellitus

6 Feb 2024

Abstract excerpt

Throughout pregnancy, some degree of insulin resistance is necessary to divert glucose towards the developing foetus. In gestational diabetes mellitus (GDM), insulin resistance is exacerbated in combination with insulin deficiency, causing new-onset maternal hyperglycaemia. The rapid reversal of insulin resistance following delivery strongly implicates the placenta in GDM pathogenesis. In this case-control study,...

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PMID: 38396626
DOI: 10.3390/ijms25041947

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