Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel BRCA2 pathogenic variant c.7094_7100del (p.His2365LeufsTer9) in an Italian family with hereditary breast cancer.

European review for medical and pharmacological sciences - 1 Feb 2024

Dell'Edera D, Allegretti A, La Rocca F, Centoducati C, Persia B

Abstract excerpt

BACKGROUND: Breast cancer is the most common type of malignancy and the foremost cause of tumor-related death in women. The two most well-known genes linked to hereditary breast cancer are BRCA1 (MIM#113705) and BRCA2 (MIM#600185). Germline mutations in the tumor-suppressor genes are found in a proportion of this group. CASE REPORT: Family history of breast and ovarian cancer, early-onset breast cancer, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 gene

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Genetic Predisposition to Disease

Share to Germ-Line Mutation

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 38375722
DOI: 10.26355/eurrev_202402_35356

Genes

BRCA2
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel BRCA2 pathogenic variant c.7094_7100del (p.His2365LeufsTer9) in an Italian family with hereditary breast cancer.PMID 38375722Read ↗

Identification of a novel in-frame deletion in BRCA2 and analysis of variants of BRCA1/2 in Italian patients affected with hereditary breast and ovarian cancer.Semantic proximity Read ↗

Clinical and molecular characterization of the BRCA2 p.Asn3124Ile variant reveals substantial evidence for pathogenic significance.Semantic proximity Read ↗

Prevalence and Spectrum of BRCA Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study.Semantic proximity Read ↗

Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer.Semantic proximity Read ↗

Genomic analysis of breast cancer patients from Kerala: A novel BRCA1 mutation detected.Semantic proximity Read ↗

Hereditary breast cancer next-generation sequencing (NGS) panel evaluation in the south region of Brazil: a novel<i>BRCA2</i>candidate pathogenic variant is reportedSemantic proximity Read ↗

Hereditary breast cancer next-generation sequencing panel evaluation in the south region of Brazil: A novel BRCA2 candidate pathogenic variant is reported.Semantic proximity Read ↗

Novel BRCA2 c.8434_8435insTT (p. Gly2812Valfs*10) mutation in a family with multiple hematologic malignancies and solid tumors.Semantic proximity Read ↗

Case report: A rare BRCA1 de novo variant in a female with breast cancerSemantic proximity Read ↗

Novel BRCA1 and BRCA2 pathogenic mutations in Slovene hereditary breast and ovarian cancer families.Semantic proximity Read ↗

A new mutation of BRCA2 gene in an Italian healthy woman with familial breast cancer history.Semantic proximity Read ↗

Identification of a novel pathogenic mutation in BRCA2 in a Spanish breast-ovarian cancer family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.