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Enterovirus A71 does not meet the uncoating receptor SCARB2 at the cell surface

15 Feb 2024

Abstract excerpt

Enterovirus A71 (EV-A71) infection involves a variety of receptors. Among them, two transmembrane protein receptors have been investigated in detail and shown to be critical for infection: P-selectin glycoprotein ligand-1 (PSGL-1) in lymphocytes (Jurkat cells), and scavenger receptor class B member 2 (SCARB2) in rhabdomyosarcoma (RD) cells. PSGL-1 and SCARB2 have been reported to be expressed on the surface of...

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PMID: 38359079
DOI: 10.1371/journal.ppat.1012022

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