Article
A novel lncRNA-hidden polypeptide regulates malignant phenotypes and pemetrexed sensitivity in A549 pulmonary adenocarcinoma cells.
Amino acids - 13 Feb 2024
Han Xiaobing, Chen Liangxin, Sun Peng, Wang Xiuqing, Zhao Qian, Liao Lingfeng, Lou Dejin, Zhou Nan, Wang Yujun
Abstract excerpt
The advance of high-throughput sequencing enhances the discovery of short ORFs embedded in long non-coding RNAs (lncRNAs). Here, we uncovered the production and biological activity of lncRNA-hidden polypeptides in lung adenocarcinoma (LUAD). In the present study, bioinformatics was used to screen the lncRNA-hidden polypeptides in LUAD. Analysis of protein expression was done by western blot or immunofluorescence...
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