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Article

Generation of two iPSC lines from Mowat-Wilson syndrome patients carrying heterozygous ZEB2 mutations.

Stem cell research - 1 Apr 2024

Gorrieri Giulia, Tamburro Serena, Baldassari Simona, Guerrisi Sara, Zara Federico, Ricci Emilia, Maria Cordelli Duccio, Scudieri Paolo, Musante Ilaria

Abstract excerpt

ZEB2 is a protein-coding gene belonging to a very restricted family of transcription factors. ZEB2 acts mainly as a transcription repressor, is expressed in various tissues and its role is fundamental for the correct development of the nervous system. The best-known clinical picture associated with ZEB2 mutations is Mowat-Wilson syndrome, caused mostly by haploinsufficiency and characterized by possible...

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PMID: 38350246
DOI: 10.1016/j.scr.2024.103333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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