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Article

Establishment of an iPSC line from a NDD patient with a heterozygous mutation in the CTNNB1 gene.

Stem cell research - 1 Sept 2024

Ning Jiaying, Zhou Tiancheng, Luo Xianqiong, Ma Jian, Zhang Zhishuai, Gao Liwei, Zhu Yanling

Abstract excerpt

CTNNB1 encodes beta-catenin, which plays a crucial role in Wnt signaling pathway. Mutations in CTNNB1 involve in tumor developing, Primary Aldosteronism, Neurodevelopmental disorders (NDDs), etc. NDDs is a class of disorders that impact brain development and function, manifesting symptom including autism spectrum disorder (ASD), intellectual disability (ID), schizophrenia (SCZ), and epilepsy. Here, we generated...

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Identifiers

PMID: 38972232
DOI: 10.1016/j.scr.2024.103487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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