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Defective autophagy and autophagy activators in myasthenia gravis: a rare entity and unusual scenario

12 Feb 2024

Abstract excerpt

Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ) that results from autoantibodies against nicotinic acetylcholine receptors (nAchRs) at NMJs. These autoantibodies are mainly originated from autoreactive B cells that bind and destroy nAchRs at NMJs preventing nerve impulses from activating the end-plates of skeletal muscle. Indeed, immune dysregulation plays a crucial role in the...

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PMID: 38346408
DOI: 10.1080/15548627.2024.2315893

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