Article
Immunoglobulin allotypes in patients in end-stage renal failure.
Journal of immunogenetics - 1 Jan 2000
Laundy G J, Bradley B A
Abstract excerpt
In a population of 282 Caucasoid patients in end-stage renal failure (ESRF) Gm and Km typing has confirmed a significant increase in the frequency of the Gm1,2,17;21 haplotype. This was confined to an increase in the number of heterozygous Gm(1,2,3,17;21,5,10,13,14) individuals. A concomitant decrease in the frequency of presumptive Gm(3,5,10,13,14) heterozygotes was also confirmed. Analysis of individual renal...
Topics
- Autoimmune Diseases
- Female
- Genotype
- Glomerulonephritis
- Haploidy
- Heterozygote
- Homozygote
- Humans
- Hypertension
- Immunoglobulin Allotypes
- Immunoglobulin G
- Kidney Failure, Chronic
