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Dementia with Lewy Bodies: Genomics, Transcriptomics, and Its Future with Data Science

25 Jan 2024

Abstract excerpt

Dementia with Lewy bodies (DLB) is a significant public health issue. It is the second most common neurodegenerative dementia and presents with severe neuropsychiatric symptoms. Genomic and transcriptomic analyses have provided some insight into disease pathology. Variants within SNCA, GBA, APOE, SNCB, and MAPT have been shown to be associated with DLB in repeated genomic studies. Transcriptomic analysis,...

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PMID: 38334615
DOI: 10.3390/cells13030223

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