Article
Genetic variants in primary cilia-related genes associated with the prognosis of first-line chemotherapy in colorectal cancer.
Cancer medicine - 1 Jan 2024
Qiu Lei, Chen Silu, Ben Shuai, Cui Jinxin, Lu Shan, Qu Rong, Lv Jinghuan, Shao Wei, Yu Qiang
Abstract excerpt
BACKGROUND: Primary cilia are antenna-like organelles that conduct physical and chemical signals, which affect cell proliferation, migration, and differentiation. Some researchers have reported the correlation between primary cilia-related genes and prognosis of colorectal cancer (CRC). METHODS: The association between single nucleotide polymorphisms (SNPs) of primary cilia-related genes and outcome after the...
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