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A new chromosome-scale duck genome shows a major histocompatibility complex with several expanded multigene families

5 Feb 2024

Abstract excerpt

BACKGROUND: The duck (Anas platyrhynchos) is one of the principal natural hosts of influenza A virus (IAV), harbors almost all subtypes of IAVs and resists to many IAVs which cause extreme virulence in chicken and human. However, the response of duck's adaptive immune system to IAV infection is poorly characterized due to lack of a detailed gene map of the major histocompatibility complex (MHC). RESULTS: We...

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PMID: 38317190
DOI: 10.1186/s12915-024-01817-0

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