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Article

Thyroid hormone links environmental signals to DNA methylation.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 25 Mar 2024

Seebacher Frank, Little Alexander G

Abstract excerpt

Environmental conditions experienced within and across generations can impact individual phenotypes via so-called 'epigenetic' processes. Here we suggest that endocrine signalling acts as a 'sensor' linking environmental inputs to epigenetic modifications. We focus on thyroid hormone signalling and DNA methylation, but other mechanisms are likely to act in a similar manner. DNA methylation is one of the most...

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Identifiers

PMID: 38310936
DOI: 10.1098/rstb.2022.0506
PMCID: PMC10838643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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