Article
LAT1-dependent placental methionine uptake is a key player in fetal programming of metabolic disease.
Metabolism: clinical and experimental - 1 Apr 2024
Schroeder Mariana, Fuenzalida Barbara, Yi Nan, Shahnawaz Saira, Gertsch Jürg, Pellegata Daniele, Ontsouka Edgar, Leiva Andrea, Gutiérrez Jaime, Müller Martin, Brocco Marcela A, Albrecht Christiane
Abstract excerpt
The Developmental Origins of Health and Disease hypothesis sustains that exposure to different stressors during prenatal development prepares the offspring for the challenges to be encountered after birth. We studied the gestational period as a particularly vulnerable window where different stressors can have strong implications for fetal programming of the offspring's life-long metabolic status via alterations...
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