Article
A SNP-based genotyping strategy to detect the abuse of homologous blood transfusion from dried blood spots.
Drug testing and analysis - 1 Nov 2024
Donati Francesco, Natalucci Alice, Concetti Livia, de la Torre Xavier, Botrè Francesco
Abstract excerpt
We performed genotyping analysis of human biallelic polymorphisms (single nucleotide polymorphisms) for the detection of homologous blood transfusion in sports doping. DNA was extracted from dried blood spots and quantified real-time fast PCR. The method was proven to allow the detection of transfusions up to a donor percentage of 1%, with a significant improvement in terms of sensitivity with respect to both the...
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