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Clinical Signs in 166 Beagles with Different Genotypes of Lafora.

Genes - 19 Jan 2024

Flegel Thomas, Dirauf Christine, Kehl Alexandra, Dietzel Josephine, Holtdirk Annette, Langbein-Detsch Ines, Müller Elisabeth

Abstract excerpt

Lafora disease (LD) is a genetic disease affecting beagles, resulting in seizures in combination with other signs. The aim of this study was to describe the clinical signs of LD in beagles with different NHLRC1 genotypes. One hundred and sixty-six beagles were tested for an NHLRC1 gene defect: L/L (n = 67), N/L (n = 32), N/N (n = 67). Owners were asked to participate in a survey about the clinical signs of LD in...

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Identifiers

PMID: 38275603
DOI: 10.3390/genes15010122
PMCID: PMC10815021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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