Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leukotriene B4 receptor knockdown affects PI3K/AKT/mTOR signaling and apoptotic responses in colorectal cancer

20 Jan 2024

Abstract excerpt

Colorectal cancer (CRC) presents a landscape of intricate molecular dynamics. In this study, we focused on the role of the leukotriene B4 receptor (LTB4R) in CRC, exploring its significance in the disease's progression and potential therapeutic approaches. Using bioinformatics analysis of the GSE164191 and the Cancer Genome Atlas-colorectal adenocarcinoma (TCGA-COAD) datasets, we identified LTB4R as a hub gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Treatments and Studies
Share to Cytokine Signaling Pathways and Interactions
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38259082
DOI: 10.17305/bb.2024.10119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leukotriene B4 receptor knockdown affects PI3K/AKT/mTOR signaling and apoptotic responses in colorectal cancerPMID 38259082Read ↗

Delineating the role of nuclear receptors in colorectal cancer, a focused reviewSemantic proximity Read ↗

Identification of molecular patterns of anoikis and epithelial-mesenchymal transition-combined index for colorectal cancer and the regulatory role of LTBP1 in colorectal cancerSemantic proximity Read ↗

Long noncoding RNA EPB41L4A‐AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancerSemantic proximity Read ↗

LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal CancerSemantic proximity Read ↗

Cetuximab inhibits colorectal cancer development through inactivating the Wnt/β-catenin pathway and modulating PLCB3 expressionSemantic proximity Read ↗

C5aR1 promotes the progression of colorectal cancer by EMT and activating Wnt/β-catenin pathwaySemantic proximity Read ↗

NOTCH4 regulates colorectal cancer proliferation, invasiveness, and determines clinical outcome of patientsSemantic proximity Read ↗

RGL2 Drives the Metastatic Progression of Colorectal Cancer via Preventing the Protein Degradation of β-catenin and KRASSemantic proximity Read ↗

NDRG4, a novel candidate tumor suppressor, is a predictor of overall survival of colorectal cancer patientsSemantic proximity Read ↗

Small Molecule Compounds of Natural Origin Target Cellular Receptors to Inhibit Cancer Development and ProgressionSemantic proximity Read ↗

NF-κB and apoptosis: colorectal cancer progression and novel strategies for treatmentSemantic proximity Read ↗

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.