Article
A four-gene signature-derived risk score for glioblastoma: prospects for prognostic and response predictive analyses
1 Aug 2019
Abstract excerpt
OBJECTIVE: Glioblastoma (GBM) is the most common primary malignant brain tumor regulated by numerous genes, with poor survival outcomes and unsatisfactory response to therapy. Therefore, a robust, multi-gene signature-derived model is required to predict the prognosis and treatment response in GBM. METHODS: Gene expression data of GBM from TCGA and GEO datasets were used to identify differentially expressed genes...