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GPCR Inhibition in Treating Lymphoma

15 Feb 2022

Abstract excerpt

G protein-coupled receptors (GPCRs) are important classes of cell surface receptors involved in multiple physiological functions. Aberrant expression, upregulation, and mutation of GPCR signaling pathways are frequent in many types of cancers, promoting hyperproliferation, angiogenesis, and metastasis. Recent studies showed that alterations of GPCRs are involved in different lymphoma types. Herein, we review the...

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PMID: 38239337
DOI: 10.1021/acsmedchemlett.1c00600

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