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Article

Somatic POLE Mutation and Ultra-Hypermutated Genotype in a De Novo High-Grade, Isocitrate Dehydrogenase Wild-Type Glioma: Treatment Implications.

JCO precision oncology - 1 Jan 2024

Mundt Daniel, Melguizo-Gavilanes Isaac, Tumu Anil Y, Dubner Steven, Walters Mary K, McFarlane Laura

Abstract excerpt

Pembrolizumab leads to a durable response in ultra-hypermutated, high-grade, glioma.

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 38237101
DOI: 10.1200/PO.23.00324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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