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Essential genes analysis reveals small ribosomal subunit protein eS28 may be a prognostic factor and potential vulnerability in osteosarcoma

15 Dec 2023

Abstract excerpt

Osteosarcoma, the most common primary malignant bone tumor, is currently treated with surgery combined with chemotherapy, but the limited availability of targeted drugs contributes to a poor prognosis. Identifying effective therapeutic targets is crucial for improving the prognosis of osteosarcoma patients. We screened the DepMap database to identify essential genes as potential therapeutic targets for...

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PMID: 38204480
DOI: 10.1016/j.jbo.2023.100517

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