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Multi-kingdom microbial signatures in excess body weight colorectal cancer based on global metagenomic analysis

5 Jan 2024

Abstract excerpt

Excess body weight (EBW) increases the risk of colorectal cancer (CRC) and is linked to lower colonoscopy compliance. Here, we extensively analyzed 981 metagenome samples from multiple cohorts to pinpoint the specific microbial signatures and their potential capability distinguishing EBW patients with CRC. The gut microbiome displayed considerable variations between EBW and lean CRC. We identify 44 and 37...

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PMID: 38182885
DOI: 10.1038/s42003-023-05714-0

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