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Causal relationship between gut microbiota and tuberculosis: a bidirectional two-sample Mendelian randomization analysis

4 Jan 2024

Abstract excerpt

BACKGROUND: Growing evidence from observational studies and clinical trials suggests that the gut microbiota is associated with tuberculosis (TB). However, it is unclear whether any causal relationship exists between them and whether causality is bidirectional. METHODS: A bidirectional two-sample Mendelian randomization (MR) analysis was performed. The genome-wide association study (GWAS) summary statistics of...

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PMID: 38178098
DOI: 10.1186/s12931-023-02652-7

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