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Article

Development and validation of epithelial mesenchymal transition-related prognostic model for hepatocellular carcinoma.

Aging - 30 Apr 2021

Wang Xuequan, Xing Ziming, Xu Huihui, Yang Haihua, Xing Tongjing

Abstract excerpt

Epithelial cell transformation (EMT) plays an important role in the pathogenesis and metastasis of hepatocellular carcinoma (HCC). We aimed to establish a genetic risk model to evaluate HCC prognosis based on the expression levels of EMT-related genes. The data of HCC patients were collected from TCGA and ICGC databases. Gene expression differential analysis, univariate analysis, and lasso combined with stepwise...

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Carcinoma, Hepatocellular
Epithelial-Mesenchymal Transition
Kaplan-Meier Estimate
Lymphocytes, Tumor-Infiltrating
Nomograms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proportional Hazards Models

Protein Interaction Maps

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PMID: 33929972
DOI: 10.18632/aging.202976
PMCID: PMC8202896

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