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Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction

15 Dec 2023

Abstract excerpt

Background Osteosarcoma is a highly aggressive type of bone cancer with a poor prognosis. In the tumor immune microenvironment, T-cell exhaustion can occur due to various factors, leading to reduced tumor-killing ability. The purpose of this study was to construct a prognostic model based on T-cell exhaustion-associated genes in osteosarcoma. Methods Patient data for osteosarcoma were retrieved from the TARGET...

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PMID: 38169731
DOI: 10.3389/fimmu.2023.1265098

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